Antiplasmodial activity of desloratadine-dihydroartemisinin-piperaquine on Plasmodium berghei infected mice
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منابع مشابه
In vivo Antiplasmodial and Cytotoxic Activity of Achyranthes aspera and Ficus thoningii in Mice Infected with Plasmodium berghei
Malaria remains o n e o f the leading causes of morbidity and mortality in tropical countries, and the alarming spread of the drugs resistant malaria parasite underscores the need to develop new antimalarial compounds. In this study, the phytochemical constituents, in vivo antiplasmodial, and cytotoxic activity of methanolic extracts of Achyranthes aspera and Ficus thoningii were evaluated usin...
متن کاملAntiplasmodial Effect of Anthocleista vogelii on Albino Mice Experimentally Infected with Plasmodium berghei berghei (NK 65)
The objective of the present study was to investigate the antiplasmodial effect of the ethanolic stem bark extract of Anthocleista vogelii at different doses in albino mice infected with Plasmodium berghei berghei (NK 65). Thirty-six mice were divided into six groups of six mice each. Five groups (B1-B3, D, and G) were infected with Plasmodium berghei berghei parasitized red blood cells. Groups...
متن کاملAntiplasmodial activity of Ajuga bracteosa against Plasmodium berghei infected BALB/c mice.
BACKGROUND & OBJECTIVES The present work was undertaken to evaluate antiplasmodial activity of ethanolic leaves extract of traditional medicinal plant Ajuga bracteosa in Plasmodium berghei infected BALB/c mice along with its phytochemical screening and acute toxicity test to support its traditional use as a remedy for malaria. METHODS Plant extract (ethanolic) 250, 500, 750 mg/kg/day was eval...
متن کاملAntiplasmodial activity of solvent fractions of methanolic root extract of Dodonaea angustifolia in Plasmodium berghei infected mice
BACKGROUND Malaria is one of the most important infectious diseases in the World. The choice for the treatment is highly limited, and several of these may eventually be lost or compromised due to drug resistance. The use of plant medicine in the treatment of malaria and its various presentations is a common practice in many countries of Africa where the disease is mostly endemic. Dodonaea angus...
متن کاملAntiplasmodial Activity of Ethanol Extract of Vernonia amygdalina leaf in Plasmodium berghei Infected Mice: in vivo study
The antiplasmodial activity of crude ethanol extract of Vernonia amygdalina leaf in Plasmodium berghei infected mice was evaluated. A total of 20 mice were randomly distributed into five groups of four mice each. The infected mice were treated immediately after inoculation with 200, 400 and 600mg/kgbw of the extract respectively. Group 4 (Positive control) was treated with standard drug (Chloro...
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ژورنال
عنوان ژورنال: Journal of Applied Biology & Biotechnology
سال: 2021
ISSN: 2455-7005,2347-212X
DOI: 10.7324/jabb.2021.9217